A CRISPR-strategy for the generation of a detectable fluorescent hESC reporter line (WAe009-A-37) for the subpallial determinant GSX2
GSX2 is a homeobox transcription factor (TF) controlling the specification of the ventral lateral ganglionic eminence and its major derivative, the corpus striatum.Medium spiny neurons (MSNs) represent click here the largest cell component of the striatum and they are primarily affected in Huntington nyx 22 brush disease (HD).Here, we used CRISPR t